haplotype

American

[hap-luh-tahyp] / ˈhæp ləˌtaɪp /

noun

Genetics. a combination of closely linked DNA sequences on one chromosome that are often inherited together.

By comparing haplotypes of a mother and father with those of a fetus, scientists can study how new genetic changes arise.

haplotype British

/ ˈhæpləʊˌtaɪp /

noun

a set of alleles inherited by an individual from a single parent

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of haplotype

First recorded in 1965–70; haplo- + type

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

The study revealed high-risk EBV haplotype present in about 70% of NPC cases, compared to about 30% of population carriers.

From Science Daily • Nov. 15, 2024

In the protected area, there was a dominance of a single mtDNA haplotype labeled as S4.

From Science Daily • Feb. 20, 2024

PmUG01 consisted of multiple haplotypes, with the majority haplotype being used for the iCORN28, and a coverage analysis was performed to remove duplicate contigs.

From Nature • Jan. 24, 2017

The advisory report suggests that haplotype matching should be considered “as a precautionary step in donor selection”, but does not recommend it be mandatory.

From Nature • Nov. 29, 2016

The inferred SNP rate for those regions is 1.3%, while for the remaining haplotype regions it is below 0.1%.

From Nature • Nov. 17, 2015

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023