Cushing's disease

American  

noun

Pathology.

1. a disease characterized by abnormal accumulations of facial and trunk fat, fatigue, hypertension, and osteoporosis, caused by hyperfunction of the adrenal cortex or administration of adrenal cortical hormones.

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Cushing's disease British  

/ ˈkʊʃɪŋz /

noun

1. a rare condition caused by excess corticosteroid hormones in the body, characterized chiefly by obesity of the trunk and face, high blood pressure, fatigue, and loss of calcium from the bones

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Etymology

Origin of Cushing's disease

1935–40; after H. W. Cushing, who first described it

Example Sentences

Hypersecretion of glucocorticoids can cause a condition known as Cushing’s disease, characterized by a shifting of fat storage areas of the body.

From Textbooks • Jun. 9, 2022

Later, her sister was diagnosed with Cushing’s disease.

From Washington Post • Jan. 20, 2022

His mother would die, from complications due to Cushing’s disease, in 2008.

From The New Yorker • Dec. 10, 2018

Ms Matthews, who grew up in Herefordshire but now lives in London, was diagnosed with Cushing's disease in 2009.

From BBC • Mar. 23, 2018

Cushing’s disease and Cushing’s syndrome — two illnesses linked to hormones gone awry — are named for his discoveries.

From New York Times • Aug. 23, 2010