occlude
verb (used with object)
to close, shut, or stop up (a passage, opening, etc.).
Used to describe actions that started in the past and continue into or have direct relevance to the present.
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
Rhodopsin and the S1P1 receptor have occluded binding pockets, presumably because they both bind hydrophobic ligands that may enter the receptor from the lipid bilayer.
From Nature ● Feb. 13, 2013