hyperplasia

American  

[hahy-per-pley-zhuh, -zhee-uh, -zee-uh] / ˌhaɪ pərˈpleɪ ʒə, -ʒi ə, -zi ə /

noun

Pathology, Biology.

1. abnormal multiplication of cells.

2. enlargement of a part due to an abnormal numerical increase of its cells.

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hyperplasia British  

/ ˌhaɪpəˈplæzɪə, ˌhaɪpəˈplæstɪk /

noun

1. enlargement of a bodily organ or part resulting from an increase in the total number of cells Compare hypertrophy

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Other Word Forms

• hyperplastic
  adjective

Etymology

Origin of hyperplasia

First recorded in 1860–65; hyper- + -plasia

Example Sentences

See Examples For:

hyperplasia

Crinetics primarily develops products to treat endocrine disorders, including acromegaly, a rare hormonal disorder caused by the overproduction of growth hormone, and congenital adrenal hyperplasia, a condition that affects the adrenal glands.

From The Wall Street Journal ● Jul. 6, 2026

Neurocrine already markets Crenessity, an oral CRF1 receptor antagonist used to treat congenital adrenal hyperplasia, which is a collection of genetic disorders affecting the adrenal glands.

From MarketWatch ● Apr. 6, 2026

These vessels were encased by CGRP+ sensory nerve fibers and were growing towards the lining fibroblasts in areas of excessive tissue growth, or hyperplasia.

From Science Daily ● Apr. 11, 2024

This side effect, called paradoxical adipose hyperplasia, usually requires surgery to correct.

From Seattle Times ● Apr. 17, 2023

It has been shown that dogs fed for a long time on putrefied meat developed inflammation and degeneration of the adventitia and media, with hyperplasia and calcification of the intima of many arteries.

From Arteriosclerosis and Hypertension: with Chapters on Blood Pressure, 3rd Edition. by Warfield, Louis Marshall