[ hahy-bri-doh-muh ]
/ ˌhaɪ brɪˈdoʊ mə /

noun, plural hy·brid·o·mas. Biotechnology.

a hybrid cell made in the laboratory by fusing a normal cell with a cancer cell, usually a myeloma or lymphoma, in order to combine desired features of each, as the ability of the cancer cell to multiply rapidly with the ability of the normal cell to dictate the production of a specific antibody.

Origin of hybridoma

First recorded in 1975–80; hybrid + -oma
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

British Dictionary definitions for hybridoma

/ (ˌhaɪbrəˈdəʊmə) /


a hybrid cell formed by the fusion of two different types of cell, esp one capable of producing antibodies, but of limited lifespan, fused with an immortal tumour cell

Word Origin for hybridoma

C20: from hybrid + -oma
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Medicine definitions for hybridoma

[ hī′brĭ-dōmə ]


A cell hybrid produced in vitro by the fusion of a lymphocyte that produces antibodies and a myeloma tumor cell. It proliferates into clones that produce a continuous supply of a specific antibody.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.