hybridoma

American  

[hahy-bri-doh-muh] / ˌhaɪ brɪˈdoʊ mə /

noun

Biotechnology.

plural

hybridomas

1. a hybrid cell made in the laboratory by fusing a normal cell with a cancer cell, usually a myeloma or lymphoma, in order to combine desired features of each, as the ability of the cancer cell to multiply rapidly with the ability of the normal cell to dictate the production of a specific antibody.

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hybridoma British  

/ ˌhaɪbrəˈdəʊmə /

noun

1. a hybrid cell formed by the fusion of two different types of cell, esp one capable of producing antibodies, but of limited lifespan, fused with an immortal tumour cell

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Etymology

Origin of hybridoma

First recorded in 1975–80; hybrid + -oma

Example Sentences

"When you make an antibody, you test what are called hybridomas, cells that produce antibodies. We screened thousands before finding the one that worked," Abdel-Mohsen said.

From Science Daily

The accidental loss of hybridoma cell lines is especially detrimental as genetic material might be unavailable to recover the coding sequence for continued antibody use.

From Scientific American

Spleen cells that had been activated upon antigen recognition fused preferentially with the myeloma cells, generating hybrid cells called hybridomas.

From Nature

A quick science lesson: A hybridoma is formed when a B cell is combined with a cancer cell.

From Washington Times

Although for many years the path toward this goal appeared to be pharmacologic in nature, four decades ago an important deviation was made: the advent of hybridoma technology.

From Science Magazine