hydrolase

[hahy-druh-leys, -leyz]

noun

Biochemistry.

1. an enzyme that catalyzes hydrolysis.

hydrolase

/ ˈhaɪdrəˌleɪz /

noun

1. an enzyme, such as an esterase, that controls hydrolysis

Word History and Origins

Origin of hydrolase¹

First recorded in 1920–25; hydr- ¹ + -ol ¹ + -ase

Example Sentences

The researchers, who published their results recently in Nature, identified a new role for an old bacterial enzyme, known as bile salt hydrolase, or BSH.

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To test their hypothesis that bile salt hydrolase is involved in the creation of bile acids, the researchers took a multipronged approach.

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Normally, they are broken down by an enzyme called fatty acid amide hydrolase, or FAAH.

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The Me-His residue in the modified enzymes acts as a nucleophilic catalyst that is broadly analogous to the nucleophilic residues found in serine hydrolase and cysteine hydrolase enzymes.

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The enzyme—organophosphorus hydrolase, or OPH, which breaks down OPs into harmless components—also worked without the cloak, but only for a few brief hours.

Read more on Scientific American