1. protected from a disease or the like, as by inoculation.
  2. of or relating to the production of antibodies or lymphocytes that can react with a specific antigen: immune reaction.
  3. exempt or protected: immune from punishment.
  4. not responsive or susceptible: immune to new ideas.
  1. a person who is immune.

Origin of immune

1400–50; late Middle English < Latin immūnis exempt, equivalent to im- im-2 + -mūnis; see common
Related formshy·per·im·mune, adjectivenon·im·mune, adjective Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018

British Dictionary definitions for hyperimmune


  1. protected against a specific disease by inoculation or as the result of innate or acquired resistance
  2. relating to or conferring immunityan immune body See antibody
  3. (usually postpositive foll by to) unsusceptible (to) or secure (against)immune to inflation
  4. exempt from obligation, penalty, etc
  1. an immune person or animal

Word Origin for immune

C15: from Latin immūnis exempt from a public service, from im- (not) + mūnus duty
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Word Origin and History for hyperimmune



mid-15c., "free; exempt," back-formation from immunity. Cf. Latin immunis "exempt from public service, free from taxes." Specific modern medical sense of "exempt from a disease" (typically because of inoculation) is from 1881. Immune system attested by 1917.

Online Etymology Dictionary, © 2010 Douglas Harper

hyperimmune in Medicine


  1. Of, relating to, or having resistance to infection by a specific pathogen.
  2. Relating to the mechanism of sensitization in which the reactivity is so altered by previous contact with an antigen that the responsive tissues respond quickly upon subsequent contact.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.