hyperkeratosis

American  

[hahy-per-ker-uh-toh-sis] / ˌhaɪ pərˌkɛr əˈtoʊ sɪs /

noun

1. Pathology.

   1. proliferation of the cells of the cornea.

   2. a thickening of the horny layer of the skin.

2. Also called x-disease.  Veterinary Pathology. a disease of cattle resulting from their physical contact with or eating of objects or food contaminated by wood preservatives or machinery lubricants containing highly chlorinated naphthalenes, characterized by thickening and hardening of the skin, abnormal secretion of tears and saliva, and diarrhea.

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hyperkeratosis British  

/ ˌhaɪpəˌkɛrəˈtɒtɪk, ˌhaɪpəˌkɛrəˈtəʊsɪs /

noun

1. pathol overgrowth and thickening of the outer layer of the skin

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Other Word Forms

• hyperkeratotic
  adjective

Etymology

Origin of hyperkeratosis

From New Latin, dating back to 1835–45; see origin at hyper-, keratosis

Example Sentences

An estimated 10,000 with hyperkeratosis have already gone through the yards.

From Time Magazine Archive

From these samples they can diagnose a severe skin disease known as epidermolytic hyperkeratosis and such blood disorders as hemophilia and thalassemia, and the 40% of sickle cell anemia cases that amniocentesis misses.

From Time Magazine Archive

In Fort Worth's stock pens, federal inspectors were carefully checking all cattle for hyperkeratosis letting them be slaughtered if not too sick.

From Time Magazine Archive

Veterinarians at first called the sickness "Disease X," finally diagnosed it as hyperkeratosis,* a poisoning caused by chlorinated naphthalene.

From Time Magazine Archive

Pathologically the first change noted in the epidermis is thought to be an acanthosis, followed by epithelial atrophy, and a hyperkeratosis, intercellular edema, and colloid degeneration of the prickle cells.

From Essentials of Diseases of the Skin Including the Syphilodermata Arranged in the Form of Questions and Answers Prepared Especially for Students of Medicine by Stelwagon, Henry Weightman