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hyperplasia

American  
[hahy-per-play-zhuh, -zhee-uh, -zee-uh] / ˌhaɪ pərˈpleɪ ʒə, -ʒi ə, -zi ə /

noun

Pathology, Biology.
  1. abnormal multiplication of cells.

  2. enlargement of a part due to an abnormal numerical increase of its cells.


hyperplasia British  
/ ˌhaɪpəˈplæzɪə /

noun

  1. enlargement of a bodily organ or part resulting from an increase in the total number of cells Compare hypertrophy

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of hyperplasia

First recorded in 1860–65; hyper- + -plasia

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Crinetics primarily develops products to treat endocrine disorders, including acromegaly, a rare hormonal disorder caused by the overproduction of growth hormone, and congenital adrenal hyperplasia, a condition that affects the adrenal glands.

From The Wall Street Journal ● Jul. 6, 2026

Neurocrine already markets Crenessity, an oral CRF1 receptor antagonist used to treat congenital adrenal hyperplasia, which is a collection of genetic disorders affecting the adrenal glands.

From MarketWatch ● Apr. 6, 2026

These vessels were encased by CGRP+ sensory nerve fibers and were growing towards the lining fibroblasts in areas of excessive tissue growth, or hyperplasia.

From Science Daily ● Apr. 11, 2024

A look at the condition, also known as benign prostatic hyperplasia:

From Seattle Times ● Jan. 26, 2024

In other animals hyperplasia progresses for a time—until the parts become greatly enlarged and conditions apparently attain an immutable state.

From Lameness of the Horse Veterinary Practitioners' Series, No. 1 by John Victor Lacroix

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