hyperplasia

American  

[hahy-per-pley-zhuh, -zhee-uh, -zee-uh] / ˌhaɪ pərˈpleɪ ʒə, -ʒi ə, -zi ə /

noun

Pathology, Biology.

1. abnormal multiplication of cells.

2. enlargement of a part due to an abnormal numerical increase of its cells.

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hyperplasia British  

/ ˌhaɪpəˈplæzɪə, ˌhaɪpəˈplæstɪk /

noun

1. enlargement of a bodily organ or part resulting from an increase in the total number of cells Compare hypertrophy

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Other Word Forms

• hyperplastic
  adjective

Etymology

Origin of hyperplasia

First recorded in 1860–65; hyper- + -plasia

Example Sentences

Neurocrine already markets Crenessity, an oral CRF1 receptor antagonist used to treat congenital adrenal hyperplasia, which is a collection of genetic disorders affecting the adrenal glands.

From MarketWatch • Apr. 6, 2026

These vessels were encased by CGRP+ sensory nerve fibers and were growing towards the lining fibroblasts in areas of excessive tissue growth, or hyperplasia.

From Science Daily • Apr. 11, 2024

The procedure, however, left her with a rare complication called paradoxical adipose hyperplasia, or overgrowth of fatty tissue.

From Salon • Sep. 21, 2023

A majority of the reports refer to hyperplasia.

From Seattle Times • Apr. 17, 2023

The inflammation is accompanied by the formation of so-called granules, and at the same time by a hyperplasia of the papillae.

From Encyclopaedia Britannica, 11th Edition, Volume 10, Slice 1 "Evangelical Church Conference" to "Fairbairn, Sir William" by Various