hyperplasia

American  

[hahy-per-pley-zhuh, -zhee-uh, -zee-uh] / ˌhaɪ pərˈpleɪ ʒə, -ʒi ə, -zi ə /

noun

Pathology, Biology.

1. abnormal multiplication of cells.

2. enlargement of a part due to an abnormal numerical increase of its cells.

---

hyperplasia British  

/ ˌhaɪpəˈplæzɪə, ˌhaɪpəˈplæstɪk /

noun

1. enlargement of a bodily organ or part resulting from an increase in the total number of cells Compare hypertrophy

---

Other Word Forms

Derived Forms

• hyperplastic
  adjective

Etymology

Origin of hyperplasia

First recorded in 1860–65; hyper- + -plasia

Example Sentences

Neurocrine already markets Crenessity, an oral CRF1 receptor antagonist used to treat congenital adrenal hyperplasia, which is a collection of genetic disorders affecting the adrenal glands.

From MarketWatch • Apr. 6, 2026

These vessels were encased by CGRP+ sensory nerve fibers and were growing towards the lining fibroblasts in areas of excessive tissue growth, or hyperplasia.

From Science Daily • Apr. 11, 2024

The word “benign” in benign prostatic hyperplasia means the prostate isn’t cancerous.

From Seattle Times • Jan. 26, 2024

The procedure, however, left her with a rare complication called paradoxical adipose hyperplasia, or overgrowth of fatty tissue.

From Salon • Sep. 21, 2023

If this influence causes stimulation of both the brain and the thyroid, its excessive action may cause impairment of the brain and also hyperplasia of the thyroid.

From Origin and Nature of Emotions by Crile, George W. (Washington)