imipramine

American  

[ih-mip-ruh-meen] / ɪˈmɪp rəˌmin /

noun

Pharmacology.

1. a tricyclic antidepressant, C 19 H 24 N 2 , used for the symptomatic relief of depression.

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imipramine British  

/ ɪˈmɪprəˌmiːn /

noun

1. a tricyclic antidepressant drug. Formula: C 19 H 24 N 2

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Etymology

Origin of imipramine

1955–60; contraction and rearrangement of iminodibenzyl and aminopropyl, components of the chemical name

Example Sentences

Another experimental drug, imipramine, was supposedly an antipsychotic, but scientists discovered in 1957 that it worked much better on people with depression.

From Time

But a new analysis of early trials of imipramine reveals that less-ill patients benefited most.

From Washington Post

But he would be dancing at the edge of science to put suicidal patients on Prozac, while patients with melancholic depression may in fact do quite well on older agents such as imipramine.

From Washington Post

On mice with late-stage tumours that had spread throughout the brain, though, imipramine had little effect.

From Economist

The new reanalysis revealed that neither Paxil nor high-dose imipramine was more effective than a placebo in the treatment of major depression in adolescents.

From US News