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immune system

American  

noun

Anatomy.
  1. a diffuse, complex network of interacting cells, cell products, and cell-forming tissues that protects the body from pathogens and other foreign substances, destroys infected and malignant cells, and removes cellular debris: the system includes the thymus, spleen, lymph nodes and lymph tissue, stem cells, white blood cells, antibodies, and lymphokines.


immune system Scientific  
  1. The body system in humans and other animals that protects the organism by distinguishing foreign tissue and neutralizing potentially pathogenic organisms or substances. The immune system includes organs such as the skin and mucous membranes, which provide an external barrier to infection, cells involved in the immune response, such as lymphocytes, and cell products such as lymphokines.

  2. See also autoimmune disease immune response


immune system Cultural  
  1. The system in the body that works to ward off infection and disease. Central to this system are the white blood cells. Some white blood cells produce antibodies in response to specific antigens that may invade the body; others function as scavengers to fight infection by destroying bacteria and removing dead cells.


Etymology

Origin of immune system

First recorded in 1960–65

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Anyone who may have been exposed to measles should immediately consult a medical professional if they are pregnant, an infant, unimmunized, or have a weakened immune system, according to the department.

From Los Angeles Times • Jun. 14, 2026

Before this study, CD99L2 was mainly recognized for its role in the immune system.

From Science Daily • Jun. 13, 2026

Rather than requiring an exact match to fentanyl's structure, the immune system generated antibodies that recognized a broader molecular signature shared by many fentanyl-related compounds.

From Science Daily • Jun. 13, 2026

But months later new healthy B cells grow – effectively resetting the immune system.

From BBC • Jun. 11, 2026

Neither did the early farmers understand that feeding children with more porridge and less breast milk would weaken their immune system, and that permanent settlements would be hotbeds for infectious diseases.

From "Sapiens: A Brief History of Humankind" by Yuval Noah Harari

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