immune system
Americannoun
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The body system in humans and other animals that protects the organism by distinguishing foreign tissue and neutralizing potentially pathogenic organisms or substances. The immune system includes organs such as the skin and mucous membranes, which provide an external barrier to infection, cells involved in the immune response, such as lymphocytes, and cell products such as lymphokines.
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See also autoimmune disease immune response
Etymology
Origin of immune system
First recorded in 1960–65
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
Anyone who may have been exposed to measles should immediately consult a medical professional if they are pregnant, an infant, unimmunized, or have a weakened immune system, according to the department.
From Los Angeles Times • Jun. 14, 2026
Before this study, CD99L2 was mainly recognized for its role in the immune system.
From Science Daily • Jun. 13, 2026
Rather than requiring an exact match to fentanyl's structure, the immune system generated antibodies that recognized a broader molecular signature shared by many fentanyl-related compounds.
From Science Daily • Jun. 13, 2026
But months later new healthy B cells grow – effectively resetting the immune system.
From BBC • Jun. 11, 2026
Neither did the early farmers understand that feeding children with more porridge and less breast milk would weaken their immune system, and that permanent settlements would be hotbeds for infectious diseases.
From "Sapiens: A Brief History of Humankind" by Yuval Noah Harari
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Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.