immune response
Americannoun
noun
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A protective response of the body's immune system to an antigen, especially a microorganism or virus that causes disease. The immune response involves the action of lymphocytes that deactivate antigens either by stimulating the production of antibodies (humoral immune response) or by a direct attack on foreign cells (cell-mediated immune response.) An inability to produce a normal immune response results in immunodeficiency diseases such as AIDS.
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See also cell-mediated immune response humoral immune response
Etymology
Origin of immune response
First recorded in 1950–55
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
RP1 is an oncolytic virus therapy that turbo-charges the immune response in people resistant to other immunotherapies.
From The Wall Street Journal • Apr. 14, 2026
In this case, the virus has been modified to replicate only inside tumor cells, causing them to burst, while simultaneously triggering a more aggressive immune response from the body’s own white blood cells.
From Barron's • Apr. 10, 2026
They also are sensitive to environmental conditions and can change chemical composition if stored at the wrong temperatures or shaken too vigorously, increasing the risk of an immune response or decreasing their effectiveness.
From Salon • Apr. 4, 2026
Pollard said: "The problem with vaccination is it doesn't protect you immediately and it takes some time after vaccination for the immune response to kick in."
From BBC • Mar. 17, 2026
In contrast, mice inoculated with the rough strain mounted an immune response and survived.
From "The Gene" by Siddhartha Mukherjee
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Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.