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immunocompromised

American  
[im-yuh-noh-kom-pruh-mahyzd] / ˌɪm jə noʊˈkɒm prə maɪzd /
immune-compromised,

adjective

  1. having a compromised or impaired immune response; immunodeficient.


immunocompromised British  
/ ˌɪmjʊnəʊˈkɒmprəmaɪzd /

adjective

  1. having an impaired immune system and therefore incapable of an effective immune response, usually as a result of disease, such as AIDS, that damages the immune system

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of immunocompromised

First recorded in 1970–75; immuno- + compromised

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Doctors and insurers face uncertainty over whether mFlusiva will be recommended only for specific people such as those who are immunocompromised.

From The Wall Street Journal Aug. 6, 2026

Legionnaires' is caused by bacteria that grow in warm water, leading to flu-like symptoms that can sometimes be fatal without treatment and for those who are immunocompromised.

From BBC Jul. 10, 2026

For people like your husband who may be immunocompromised and anxious, these delays can make everything appear worse.

From MarketWatch May 1, 2026

Anyone can contract human metapneumovirus, but those who are immunocompromised or have other underlying medical conditions are at particular risk of developing severe disease — including pneumonia.

From Los Angeles Times Mar. 4, 2026

Wasn’t the mom with cancer supposed to be home, in isolation, immunocompromised?

From "Not Nothing" by Gayle Forman

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