indomethacin

American  

[in-doh-meth-uh-sin] / ˌɪn doʊˈmɛθ ə sɪn /

noun

Pharmacology.

1. a substance, C 19 H 16 ClNO 4 , with anti-inflammatory, antipyretic, and analgesic properties: used in the treatment of certain kinds of arthritis and gout.

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indomethacin British  

/ ˌɪndəʊˈmɛθəsɪn /

noun

1. a drug administered orally to relieve pain, fever, and inflammation, esp in rheumatoid arthritis. Formula: C 19 H 16 ClNO 4

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Etymology

Origin of indomethacin

First recorded in 1963; indo(le) + meth(yl) + ac(etic) + -in ²

Example Sentences

Participants found ketorolac helpful 62% of the time, indomethacin was helpful 57% of the time, and diclofenac was helpful 56% of the time.

From Science Daily • Nov. 29, 2023

Researchers were quick to argue that this class-wide ban would cover substances that already exist as medicines, such as the anti-inflammatory drug indomethacin.

From Scientific American • Jan. 5, 2022

Gervais, whose test was negative, said she was elated to receive a provisional diagnosis and even happier shortly after starting a potent anti-inflammatory drug called indomethacin.

From Washington Post • Nov. 12, 2021

Even medium doses of indomethacin and etoricoxib were associated with increased risk, the study said, but there was no evidence that celecoxib increased the risk of admission for heart failure at commonly-used doses.

From The Guardian • Sep. 28, 2016

The investigators cautioned, however, that the study excluded patients with a history of upper gastrointestinal bleeding, and noted earlier research had linked indomethacin to a higher risk for major complications, including gastrointestinal discomfort.

From US News • Feb. 23, 2016