DNA repair
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"Many of these enzymes synthesize essential building blocks of life, and their nuclear localization is associated with DNA repair. Their presence in the nucleus may therefore directly shape how cancer cells respond to genotoxic stress, a hallmark of many chemotherapeutic treatments. It's an entirely new world to explore," says Dr. Sara Sdelci, corresponding author of the study and researcher at the Centre for Genomic Regulation.
From Science Daily
Some therapies target metabolic processes in cancer cells, while others focus on disrupting DNA repair systems.
From Science Daily
Using machine learning and other advanced analytical methods, the team identified a distinct pattern of gene activity related to DNA repair and stress response.
From Science Daily
The study Longitudinal assessment of DNA repair signature trajectory in prodromal versus established Parkinson's disease has been published in npj Parkinson's Disease.
From Science Daily
One surprising result was that the same DNA repair genes did not behave uniformly.
From Science Daily
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