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• LSD
  LSD

  abbreviation

  a crystalline solid, C 20 H 25 N 3 O, the diethyl amide of lysergic acid, a powerful psychedelic drug that produces temporary hallucinations and a schizophrenic psychotic state.
• L.S.D.
  L.S.D.

  abbreviation

  pounds, shillings, and pence.

LSD

¹ American  

abbreviation

Pharmacology.

1. a crystalline solid, C 20 H 25 N 3 O, the diethyl amide of lysergic acid, a powerful psychedelic drug that produces temporary hallucinations and a schizophrenic psychotic state.

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LSD ² American  

abbreviation

U.S. Navy.

• LSDs
  plural

1. a seagoing, amphibious ship capable of carrying and launching assault landing craft from a large, inner compartment that can be flooded, and of making emergency repairs at sea to smaller ships.

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LSD ³ American  

abbreviation

1. least significant digit.

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L.S.D. ⁴ American  

Or £.s.d.,

abbreviation

1. pounds, shillings, and pence.

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L.S.D. ¹ British  

abbreviation

1. librae, solidi, denarii

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LSD ² British  

noun

1. Informal name (as an illegal hallucinogen): acid.  lysergic acid diethylamide; a crystalline compound prepared from lysergic acid, used in experimental medicine and taken illegally as a hallucinogenic drug

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LSD Scientific  

/ ĕl′ĕs-dē′ /

1. Short for lysergic acid diethylamide. A crystalline compound that is a synthetic derivative of lysergic acid. It is used as a powerful hallucinogenic drug. Chemical formula: C ₂₀ H ₂₅ N ₃ O.

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LSD Cultural  

1. A drug, lysergic acid diethylamide, that produces hallucinations similar to those of a psychosis. Persons on LSD “trips,” which may last for many hours, undergo distortions of their perceptions of space and time and may lose all contact with reality.

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Etymology

Origin of LSD¹

First recorded in 1945–50; abbreviaion of German Lysergsäure-Diäthylamid “lysergic acid diethylamide”

Origin of LSD²

First recorded in 1940–45; abbreviation of l(anding), s(hip), d(ock)

Origin of L.S.D.⁴

From Latin lībrae “pounds (sterling),” see libra ¹ ( def. ), pound ² ( def. ); solidī , see solidus ¹ ( def. ); dēnāriī see denarius ( def. )

Example Sentences

See Examples For:

LSD L.S.D.

We have literally and metaphorically tried to erase our actual history in favor of a mythical past that never existed — even in bad LSD trips.

From Salon ● Aug. 7, 2026

It is so obsessively and addictively wild that its tamest moments sound like Richard Strauss on LSD.

From Los Angeles Times ● Jul. 2, 2026

Croatia's preventive vaccination, after EU approval, meant LSD was never reported in the country, despite outbreaks nearby in Serbia and Montenegro.

From Barron's ● Dec. 17, 2025

In the end, Mead appears not to have taken LSD.

From Slate ● Feb. 10, 2024

Born in New York, Mayers was one of the biggest break-out stars of the 2010s, earning eight platinum singles in the US including Wild For The Night, Everyday, LSD and A$AP Forever.

From BBC ● Apr. 21, 2022

The main dining room and its mezzanine, seating 300, and the rooftop bar and restaurant, with another 150 seats, specialize in unusual dumplings and what Mr. Morfogen calls L.S.D.: lobster, steak and Peking duck.

From New York Times ● Mar. 8, 2022

Last week Arthur Miller for the second time forced an avant-garde Manhattan theater troupe, the Wooster Group, to stop using portions of his play The Crucible in a production called L.S.D.

From Time Magazine Archive

Jones sorter set 'is cap at me; I earn good money I do; But love as follows L.S.D. 's all fol-der-riddle-dido!

From Punch, or the London Charivari, Vol. 105, August 26th 1893 by Various

Of this havresack there have been some smart carriers— I'll make 'em sit up, though, the L.S.D.

From Punch, or the London Charivari, Volume 100, February 14, 1891 by Various