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glucagon

American  
[gloo-kuh-gon] / ˈglu kəˌgɒn /

noun

Biochemistry.
  1. a hormone secreted by the pancreas that acts in opposition to insulin in the regulation of blood glucose levels.


glucagon British  
/ -ɡən, ˈɡluːkəˌɡɒn /

noun

  1. a polypeptide hormone, produced in the pancreas by the islets of Langerhans, that stimulates the release of glucose into the blood Compare insulin

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

glucagon Scientific  
/ glo̅o̅kə-gŏn′ /
  1. A polypeptide hormone produced by the pancreas that stimulates an increase in blood glucose levels, thus opposing the action of insulin.


Etymology

Origin of glucagon

1923; probably gluc- + Greek ágōn present participle of ágein to lead, drive; see -agogue

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Retatrutide is a so-called triple hormone receptor agonist, which works by activating the body’s receptors for glucagon-like peptide-1, or GLP-1, glucose-dependent insulinotropic polypeptide and glucagon, hormones that regulate blood sugar and digestion.

From The Wall Street Journal May 21, 2026

Lilly is also developing a highly efficacious injection called retatrutide that targets GIP and GLP-1 — both of which are activated by tirzepatide — in addition to glucagon.

From MarketWatch Apr. 1, 2026

UBT251 is what’s known as a triple G weight-loss agonist—meaning it combines the hormones GLP-1, GIP, and glucagon.

From Barron's Feb. 24, 2026

Laila Soueif was hospitalised last Thursday and given glucagon, a hormone used to treat severe hypoglycaemia.

From BBC Jun. 3, 2025

"The organization of the DNA around the insulin and glucagon genes was very clearly different between the two bat species," Gordon said.

From Science Daily Jan. 9, 2024

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