G-protein

American  

noun

• G-proteins
  plural

1. Biochemistry. any of a class of proteins in the membrane of a cell that mediate between hormone receptors on the cell surface and enzymes whose response allows the cell to regulate its metabolism.

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G-protein Scientific  

/ jē′prō′tēn′ /

1. Any of a class of cell membrane proteins that function as intermediaries between hormone receptors and enzymes that enable the cell to regulate its metabolism in response to hormonal changes.

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Other Word Forms

Noun Inflected Forms

• G-proteins
  plural

Example Sentences

See Examples For:

G-protein G-proteins

"G-protein coupled receptors, normally, can be activated by specific small molecules that bind in a pocket in the receptor," explained Nicholas Kalogriopoulos, a postdoctoral fellow in the Ting lab and co-lead author of the paper.

From Science Daily ● Dec. 4, 2024

This region is critical to form a signaling complex, which helps to transfer the signal from the taste receptor to the G-protein to the taste receptor cells.

From Science Daily ● Apr. 10, 2024

"We also have the ability to affect specific G-protein subtypes, like G-protein alpha or G-protein beta, rather than other G-protein pathways that we don't want to cause any other side effects."

From Science Daily ● Apr. 10, 2024

The activated G-protein in turn activates a membrane-bound enzyme called adenylyl cyclase.

From Textbooks ● Jun. 9, 2022

The subunits of the G-protein then split into the α subunit and the βγ subunit.

From Textbooks ● Jun. 9, 2022

"One class of such promising agents is the PCAIs that were designed to target oncogenic G-proteins in a manner that is different from the KRASG12C-targeting drugs."

From Science Daily ● Jun. 29, 2026

Their analysis confirmed that GPR156 activation hinges on its interaction with abundant lipids in the cell membrane, triggering structural shifts upon engagement with G-proteins in the cytoplasm.

From Science Daily ● Apr. 15, 2024

Notably, unlike conventional GPCRs, GPR156 exhibits flexibility in altering the structure of the seventh helix as it traverses the cell membrane, thereby facilitating binding with G-proteins and orchestrating signal activation to detect sound.

From Science Daily ● Apr. 15, 2024

When a hormone binds to its membrane receptor, a G- protein that is associated with the receptor is activated; G-proteins are proteins separate from receptors that are found in the cell membrane.

From Textbooks ● Jun. 9, 2022

The binding of a hormone at a single receptor causes the activation of many G-proteins, which activates adenylyl cyclase.

From Textbooks ● Jun. 9, 2022