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  • main line
    main line
    noun
    a principal line or route of a railroad, as contrasted with a branch or secondary one.
  • Main Line
    Main Line
    noun
    a fashionable residential district west of Philadelphia.
Synonyms

main line

1 American  

noun

  1. a principal line or route of a railroad, as contrasted with a branch or secondary one.

  2. a principal highway.

  3. Slang.

    1. a prominent and readily accessible vein of the body that may be used for a narcotic's injection.

    2. the act of mainlining.


Main Line 2 American  

noun

  1. a fashionable residential district west of Philadelphia.

  2. any fashionable district where socially prominent people live.


main line British  

noun

  1. railways

    1. the trunk route between two points, usually fed by branch lines

    2. ( as modifier )

      a main-line station

  2. a main road

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

verb

  1. slang (intr) to inject a drug into a vein

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

adjective

  1. having an important position, esp having responsibility for the main areas of activity

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of main line

First recorded in 1835–45

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Rupireddy called Late Stage’s main line dozens of times, but he said no one answered.

From The Wall Street Journal Aug. 6, 2026

The plans follow a trial of satellite connectivity across operators including LNER, South Western Railway and Great Western Railway, with the technology to be rolled out across nationalised main line services through funding worth £57m.

From BBC May 26, 2026

Pike followed the main line — called the trunk line — which had hoses branching off in other directions.

From Los Angeles Times Mar. 11, 2026

Trials have been done using "ropeless creels" which have the main line in a container along with a buoy and these are lowered to the seabed with the creels.

From BBC Mar. 6, 2025

We could avoid the main line of the retreat by keeping to the secondary roads beyond Udine.

From "A Farewell To Arms" by Ernest Hemingway

Network Rail has warned that the Midland Main Line will remain closed to East Midlands Railway and Thameslink services until the end of the week.

From BBC Jun. 24, 2026

In suburbs including Philadelphia’s Main Line, moms and dads are pleading with districts to rein in tech: “These electronics have ruined parenting.”

From The Wall Street Journal Jun. 22, 2026

Cardinale grew up in Villanova, Penn., an affluent suburb on Philadelphia’s Main Line, and attended The Haverford School, an all-boys prep school.

From The Wall Street Journal Jan. 16, 2026

The operator said services along the Highland Main Line, between Inverness and Perth, was running.

From BBC Jan. 5, 2026

It’s on the prestigious Main Line, just twenty-five minutes outside Philadelphia, on a rolling campus surrounded by overgrown foliage.

From "The Other Wes Moore: One Name, Two Fates" by Wes Moore

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