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margin of safety

American  

noun

Pharmacology.
  1. therapeutic index.


Etymology

Origin of margin of safety

1885–90, for an earlier sense

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Some filers try to leave a “margin of safety” to avoid triggering a higher tier.

From The Wall Street Journal

Processors may treat milk beyond minimum times or temperatures to provide an extra margin of safety, or to reduce bacteria that can cause milk to spoil, thus increasing the product's shelf life.

From Salon

He said the union spoke recently with senior management, “and management’s initial response to our request was encouraging. We fully intend to do everything we can to assure that American maintains strong margins of safety.”

From Seattle Times

The panel said aviation’s margin of safety is shrinking.

From Seattle Times

The group said Wednesday that the margin of safety in the nation’s airspace is eroding and will get worse if nothing is done.

From Seattle Times