margin of safety

noun

Pharmacology.

1. therapeutic index.

Word History and Origins

Origin of margin of safety¹

1885–90, for an earlier sense

Example Sentences

Processors may treat milk beyond minimum times or temperatures to provide an extra margin of safety, or to reduce bacteria that can cause milk to spoil, thus increasing the product's shelf life.

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He said the union spoke recently with senior management, “and management’s initial response to our request was encouraging. We fully intend to do everything we can to assure that American maintains strong margins of safety.”

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The panel said aviation’s margin of safety is shrinking.

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The group said Wednesday that the margin of safety in the nation’s airspace is eroding and will get worse if nothing is done.

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A limit of 55 to 60 parts per billion “is more likely to be protective and to provide an adequate margin of safety,” the panel said.

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