[ meg-uh-luh-blast ]
/ ˈmɛg ə ləˌblæst /
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noun Pathology.

an abnormally large, immature, and dysfunctional red blood cell found in the blood of persons with pernicious anemia or certain other disorders.



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Origin of megaloblast

First recorded in 1895–1900; megalo- + -blast
meg·a·lo·blas·tic, adjective
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2021
  • In agreement with this, "blood crises" are not to be observed in the megaloblastic anæmias.

  • We can now say that the megaloblastic metamorphosis is not a purposeful process, and for the following reasons: 1.

  • For this reason, the prognosis of megaloblastic anæmia, apart from the group of Bothriocephalus anæmia, is exceedingly bad.

  • Since the fresh formation of red blood corpuscles by means of the megaloblastic method is clearly much slower.

British Dictionary definitions for megaloblast

/ (ˈmɛɡələʊˌblɑːst) /


an abnormally large red blood cell precursor, present in certain types of anaemia
megaloblastic (ˌmɛɡələʊˈblæstɪk), adjective
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Medical definitions for megaloblast

[ mĕgə-lō-blăst′ ]


An abnormally large nucleated red blood cell found especially in pernicious anemia or in certain vitamin deficiencies.
meg′a•lo•blastic adj.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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