metastasis
Americannoun
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metastases
plural
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Pathology.
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the transference of disease-producing organisms or of malignant or cancerous cells to other parts of the body by way of the blood or lymphatic vessels or membranous surfaces.
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the condition produced by this.
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Rhetoric. a rapid transition, as from one subject to another.
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Physics. a change in position or orbit of an elementary particle.
noun
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pathol the spreading of a disease, esp cancer cells, from one part of the body to another
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a transformation or change, as in rhetoric, from one point to another
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a rare word for metabolism
Other Word Forms
Derived Forms
Inflected Forms
Nouns
Etymology
Origin of metastasis
First recorded in 1580–90, metastasis is from the Greek word metástasis “a changing”; see meta-, stasis
Explanation
When a doctor uses the word metastasis, it's never good news. It means an illness has spread to new parts of the body. The noun metastasis is a medical term that's most often used to describe a spreading cancer. If a patient's lung cancer spreads to his heart or to his lymph nodes, that is metastasis. It's a Greek word meaning "transference or change." In Latin, the word metastasis was at one time used to mean "a sudden transition in subjects," but ever since the 1660s, the English use has been almost entirely medical.
Vocabulary lists containing metastasis
Cell Biology - Middle School
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Cell Biology - High School
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Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
See Examples For:
Chronically high IL-6 levels have also been linked to recurrence and metastasis of multiple types of cancer.
From Los Angeles Times ● Jun. 15, 2026
"This could suggest that, to develop treatments for pancreatic cancer metastasis, the gene may not need to be entirely shut down to have a positive effect," says Feinberg.
From Science Daily ● Apr. 7, 2026
One triggered epithelial-mesenchymal transition, an essential step in cancer progression and metastasis.
From Science Daily ● Feb. 17, 2026
Taken together, the results point to a previously underappreciated gut-bone marrow-liver metastasis axis.
From Science Daily ● Jan. 23, 2026
Thus when the liver is torpid, a perpetual uneasiness and depression of spirits occur; which a fit of gout is supposed to cure by a metastasis of the disease.
From Zoonomia, Vol. II Or, the Laws of Organic Life by Darwin, Erasmus
Three weeks later, she learnt she actually had stage three cancer with limited metastases.
From Barron's ● Feb. 15, 2026
These monocytes normally help cancer cells evade immune defenses and support the growth of metastases.
From Science Daily ● Jan. 23, 2026
Lung metastases indicate that cancer has entered the bloodstream and are linked to worse outcomes for patients.
From Science Daily ● Jan. 22, 2026
Even in mice with advanced disease and existing metastases, the antibody improved the balance between M1 and M2 macrophages.
From Science Daily ● Jan. 22, 2026
After such free removal these tumours show little tendency to recur and metastases are rare.
From Manual of Surgery Volume Second: Extremities—Head—Neck. Sixth Edition. by Miles, Alexander
Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.
