methotrexate

[ meth-oh-trek-seyt ]

nounPharmacology.

a toxic folic acid analogue, C20H22N8O5, that inhibits cellular reproduction, used primarily in the treatment of psoriasis and certain cancers and as an immunosuppressive agent.

Origin of methotrexate

1950–55; metho(xy)- + trexate, of unclear derivation

Words Nearby methotrexate

Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2023

How to use methotrexate in a sentence

According to a recent statement from the Arthritis Foundation, people in states like Texas are reporting difficulties getting their prescriptions for methotrexate filled.
Abortion bans are impeding access to ulcer, arthritis, and cancer medications | Kate Baggaley | August 1, 2022 | Popular-Science
Soon after she started taking the drug methotrexate in February, Jennifer Crow noticed a significant improvement in her inflammatory arthritis pain.
Abortion Restrictions May Be Making It Harder for Patients to Get a Cancer and Arthritis Drug | Jamie Ducharme | July 6, 2022 | Time
Murphy says reports of patients being denied methotrexate are anecdotal, so it’s hard to get a handle on how common they are.
Abortion Restrictions May Be Making It Harder for Patients to Get a Cancer and Arthritis Drug | Jamie Ducharme | July 6, 2022 | Time

British Dictionary definitions for methotrexate

methotrexate

/ (ˌmɛθəʊˈtrɛkseɪt, ˌmiːθəʊ-) /

noun

an antimetabolite drug used in the treatment of certain cancers. Formula: C 20 H 22 N 8 O 5

Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Scientific definitions for methotrexate

methotrexate

[ mĕth′ə-trĕk′sāt ]

A toxic drug that acts as a folic acid antagonist to interfere with cellular reproduction and is used in the treatment of psoriasis, certain cancers, and certain inflammatory diseases, such as rheumatoid arthritis. Chemical formula: C20H22N8O5.

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