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methotrexate
[ meth-oh-trek-seyt ]
/ ˌmɛθ oʊˈtrɛk seɪt /
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noun Pharmacology.
a toxic folic acid analogue, C20H22N8O5, that inhibits cellular reproduction, used primarily in the treatment of psoriasis and certain cancers and as an immunosuppressive agent.
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Origin of methotrexate
1950–55; metho(xy)- + trexate, of unclear derivation
Words nearby methotrexate
methodize, methodological, methodology, methohexital, methoprene, methotrexate, methought, methoxide, methoxsalen, methoxy, methoxybenzene
Dictionary.com Unabridged
Based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
How to use methotrexate in a sentence
According to a recent statement from the Arthritis Foundation, people in states like Texas are reporting difficulties getting their prescriptions for methotrexate filled.
Abortion bans are impeding access to ulcer, arthritis, and cancer medications|Kate Baggaley|August 1, 2022|Popular-ScienceSoon after she started taking the drug methotrexate in February, Jennifer Crow noticed a significant improvement in her inflammatory arthritis pain.
Abortion Restrictions May Be Making It Harder for Patients to Get a Cancer and Arthritis Drug|Jamie Ducharme|July 6, 2022|TimeMurphy says reports of patients being denied methotrexate are anecdotal, so it’s hard to get a handle on how common they are.
Abortion Restrictions May Be Making It Harder for Patients to Get a Cancer and Arthritis Drug|Jamie Ducharme|July 6, 2022|Time
British Dictionary definitions for methotrexate
methotrexate
/ (ˌmɛθəʊˈtrɛkseɪt, ˌmiːθəʊ-) /
noun
an antimetabolite drug used in the treatment of certain cancers. Formula: C 20 H 22 N 8 O 5
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
Scientific definitions for methotrexate
methotrexate
[ mĕth′ə-trĕk′sāt ]
A toxic drug that acts as a folic acid antagonist to interfere with cellular reproduction and is used in the treatment of psoriasis, certain cancers, and certain inflammatory diseases, such as rheumatoid arthritis. Chemical formula: C20H22N8O5.
The American Heritage® Science Dictionary
Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.