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methylate

American  
[meth-uh-leyt] / ˈmɛθ əˌleɪt /

noun

  1. Also called methoxide.  any derivative of methyl alcohol, as sodium methylate, CH 3 ONa.

  2. any compound containing the methyl group.

verb (used with object)

methylated, methylating

  1. (in a compound) to replace (one or more hydrogen atoms) with the methyl group.

  2. to mix with methyl alcohol, as in the denaturation of ethyl alcohol.

methylate British  
/ ˈmɛθɪˌleɪt /

verb

  1. (tr) to mix with methanol

  2. to undergo or cause to undergo a chemical reaction in which a methyl group is introduced into a molecule

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

noun

  1. another name for methoxide

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
methylate Scientific  
/ mĕth′ə-lāt′ /

  1. An organic compound having the general formula CH 3 OR, in which R is a metal. Methylates are formed by replacing the hydrogen of the hydroxyl group (OH) of methyl alcohol with a metal.

  1. To combine with the methyl radical.

Other Word Forms

  • methylation noun
  • methylator noun
  • unmethylated adjective

Etymology

Origin of methylate

First recorded in 1825–35; methyl- + -ate 1

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

RBPs methylate miRNA to inhibit its function and thus stop mRNA degradation.

From Textbooks • Jun. 9, 2022

Well-dried hydroxylamine hydrochloride is dissolved in methyl alcohol and mixed with sodium methylate; a solution of methyldichloramine in absolute ether is then added and an ethereal solution of diazomethane distils over.

From Encyclopaedia Britannica, 11th Edition, Volume 8, Slice 4 "Diameter" to "Dinarchus" by Various

The preliminary experiments showed that condensation with sodium methylate takes a long time and gives a product which it is difficult to handle in large quantities.

From Organic Syntheses by Conant, James Bryant

They form unstable addition products with sodium ethylate or methylate.

From Encyclopaedia Britannica, 11th Edition, Volume 9, Slice 7 "Equation" to "Ethics" by Various

The latter is then made to methylate a product, aniline, derived indirectly from coal-tar.

From Coal and What We Get from It by Meldola, Raphael

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023

Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.