mono
noun
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mono
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mono-
mono-a combining form meaning “alone,” “single,” “one” (monogamy ); specialized in some scientific terms to denote a monomolecular thickness (monolayer ) and adapted in chemistry to apply to compounds containing one atom of a particular element (monohydrate ).
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mono–
mono–A prefix that means “one, only, single,” as in monochromatic, having only one color. It is often found in chemical names where it means “containing just one” of the specified atom or group, as in carbon monoxide, which is carbon attached to a single oxygen atom.
mono
1 American
[mon-oh]
/ ˈmɒn oʊ /
noun
Informal.
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monos
plural
mono
2
American
[mon-oh]
/ ˈmɒn oʊ /
adjective
mono-
3
American
especially before a vowel,
mon-
mono
1
British
/ ˈmɒnəʊ /
adjective
noun
mono-
2
British
combining form
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one; single
monochrome
monorail
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indicating that a chemical compound contains a single specified atom or group
monoxide
mono–
Scientific
Usage
What does mono- mean? Mono- is a combining form used like a prefix meaning “alone, singular, one.” It is used in a great many technical and scientific terms, including in chemistry, where it refers to compounds containing one atom of a particular element. Mono- comes from the Greek mónos, meaning “alone."What are variants of mono-?When combined with words or word elements that begin with a vowel, mono- becomes mon-, as in monacid.
Other Word Forms
Noun Inflected Forms
Etymology
Origin of mono1
By shortening
Origin of mono2
By shortening
Origin of mono-3
From Greek, combining form of mónos “alone”
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
See Examples For:
Early in his career, most albums were sold in two versions, mono and a more-expensive stereo format—a practice he described as expensive and wasteful in his autobiography.
From The Wall Street Journal ● Jun. 22, 2026
Eventually we learned I had an immune condition; I also had mono, which felt cosmically unfair considering I had not yet been kissed and suspected I’d contracted it from the skating rink water fountain.
From Salon ● Mar. 31, 2026
It so happened the Cal baseball writer had just come down with mono.
From Seattle Times ● Nov. 10, 2023
Director Peter Jackson and his team developed new software that allowed them to "de-mix" mono recordings from the 1970s to isolate individual instruments and vocals.
From BBC ● Oct. 26, 2023
“Yes, the symptoms of mono include reacting to things that aren’t there, screaming for no reason at all, and flailing on the ground like you’re about to be ax murdered.”
From "Made You Up" by Francesca Zappia
In fact, these oils contain a low amount - 5-10% - of unhealthy saturated fats and are high in healthier mono- and polyunsaturated fats.
From BBC ● Oct. 1, 2025
But typically bread only uses mono- or diglyceride fatty acids as emulsifiers, which have not been linked to risk of disease.
From Salon ● Jun. 14, 2023
This meant that simple foods like nuts, olive oil and salmon could not call themselves “healthy,” because they were too high in fat, even though it’s heart-healthy mono- and polyunsaturated fat.
From Seattle Times ● Oct. 10, 2022
Mavila, S., Rozenberg, I. & Lemcoff, N. G. A general approach to mono- and bimetallic organometallic nanoparticles.
From Nature ● Nov. 28, 2017
Their shirts were mono- grammed and their fingernails manicured.
From "I Know Why the Caged Bird Sings" by Maya Angelou
Whether his actual first words were, as his mother likes to remember, monos mou, "all by myself," they have become the memory that gives her son his identity.
From Time Magazine Archive
"How did you know the beasts were called monos?"
From Westward Ho!, or, the voyages and adventures of Sir Amyas Leigh, Knight, of Burrough, in the county of Devon, in the reign of her most glorious majesty Queen Elizabeth by Charles Kingsley
Monadelpha is from monos, one and adelphos, brother.
From The Mushroom, Edible and Otherwise Its Habitat and its Time of Growth by Miron Elisha Hard
The reason why the machine is called a monotype is that the letters are made one at a time, and monos is the Greek word for one.
From Makers of Many Things by Eva March Tappan
The word monologue comes from the combination of two Greek words, monos, alone, and legein, to speak.
From Writing for Vaudeville by Brett Page
Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.
