monoamine

American  

[mon-oh-uh-meen, -am-in] / ˌmɒn oʊ əˈmin, -ˈæm ɪn /

noun

Biochemistry.

1. any of various biogenic amine neurotransmitters having a single amino group, as dopamine, epinephrine, and norepinephrine.

---

monoamine British  

/ ˌmɒnəʊˈeɪmiːn /

noun

1. a substance, such as adrenaline, noradrenaline, or serotonin, that contains a single amine group

---

monoamine Scientific  

/ mŏn′ō-ăm′ēn,-ə-mēn′ /

1. An amine compound containing one amino group (NH ₂), especially such a compound that functions as a neurotransmitter. The catecholamines and serotonin are monoamines. Abnormal levels of monoamines in the brain have been implicated in mood disorders.

---

Etymology

Origin of monoamine

First recorded in 1855–60; mono- + amine

Example Sentences

In other words, serotonin's influence on depression, also known as the monoamine model of depression, seems to be wrong or at least incomplete.

From Salon • Feb. 20, 2023

Some research supports the “classic monoamine hypothesis,” which suggests that depression is caused by a decrease in norepinephrine and serotonin neurotransmission.

From Textbooks • Jun. 9, 2022

Ingested on its own, it has no effect on humans, because it is rapidly degraded by an enzyme in the gut, monoamine oxidase.

From The New Yorker • Sep. 5, 2016

Histamine uptake by human endometrial cells expressing the organic cation transporter EMT and the vesicular monoamine transporter-2.

From Scientific American • Sep. 5, 2012

One gene that has been linked to violence regulates the production of the monoamine oxidase A enzyme, which controls the amount of serotonin in the brain.

From New York Times • Jun. 19, 2011