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monovalent

American  
[mon-uh-vay-luhnt] / ˌmɒn əˈveɪ lənt /

adjective

  1. Chemistry. univalent.

  2. Immunology.

    1. containing only one kind of antibody.

    2. pertaining to an antibody fragment with one antigen-binding site.


monovalent British  
/ ˌmɒnəʊˈveɪlənt /

adjective

  1. Also: univalent. chem

    1. having a valency of one

    2. having only one valency

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

monovalent Scientific  
/ mŏn′ə-vā′lənt /
  1. Having a valence of 1; univalent.

  2. Containing antigens from a single strain of a microorganism or virus. Used of a vaccine or serum.


Other Word Forms


Etymology

Origin of monovalent

First recorded in 1865–70; mono- + -valent


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

“Use of monovalent vaccines also would increase the number of injections a child would need and increase the number of visits required to complete the vaccination series.”

From Los Angeles Times ● Aug. 12, 2026

But those with the newer monovalent vaccine had 3.5x higher levels of antibodies against the XBB and BQ.1.1 strains after their booster vaccination.

From Science Daily ● Mar. 12, 2024

Tan said he agrees that a monovalent is best, in part because it's easier to produce and will be more accessible in countries of lower socioeconomic status.

From Salon ● Jun. 4, 2023

It has found that monovalent vaccines against Omicron perform somewhat better than those that include the ancestral strain.

From Science Magazine ● May 22, 2023

The effectiveness of the various electrolytes in bringing about this change is proportional to their valency; bivalent ions are from 70 to 80 times, and trivalent ions about 600 times as effective as monovalent ions.

From The Chemistry of Plant Life by Roscoe Wilfred Thatcher

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