[mon-uh-vey-luh nt]
  1. Chemistry. univalent.
  2. Immunology.
    1. containing only one kind of antibody.
    2. pertaining to an antibody fragment with one antigen-binding site.

Origin of monovalent

First recorded in 1865–70; mono- + -valent
Related formsmon·o·va·lence, mon·o·va·len·cy, noun Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018

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British Dictionary definitions for monovalent


  1. chem
    1. having a valency of one
    2. having only one valency
    Also: univalent
Derived Formsmonovalence or monovalency, noun
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

monovalent in Medicine


  1. Able to form only one covalent or ionic bond.
  2. Having a valence of one; univalent.
  3. Of or relating to an antiserum containing an antibody or antibodies specific for one antigen.
  4. Containing antigens from a single strain of a microorganism.
  5. Having only one site of attachment. Used of an antibody or antigen.
Related formsmon′o•valence null n.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.

monovalent in Science


  1. Having a valence of 1; univalent.
  2. Containing antigens from a single strain of a microorganism or virus. Used of a vaccine or serum.
The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.