mutagenesis

[myoo-tuh-jen-uh-sis]

noun

1. the origin and development of a mutation.

mutagenesis

/ ˌmjuːtəˈdʒɛnɪsɪs /

noun

1. genetics the generation, usually intentional, of mutations

Other Word Forms

• mutagenetic adjective

Word History and Origins

Origin of mutagenesis¹

From New Latin, dating back to 1950–55; mutation, -genesis

Word History and Origins

Origin of mutagenesis¹

C20: from _mutation + _-genesis

Example Sentences

The researchers used site-specific mutagenesis to gain new insights into how the cofactor precursor is integrated into the enzyme and how individual amino acids are involved in anchoring and synthesis.

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The paper, "Base editing mutagenesis maps functional alleles to tune human T cell activity," was published in Nature on December 13.

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"Xiangyu's comprehensive study of the structure highlights the advantage that a targeted, structurally guided approach has over large and costly random mutagenesis screening."

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“That is what we term lethal mutagenesis,” he adds.

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The use of this technique could be seen as a weakness of Wang and co-workers’ approach, because unnatural-amino-acid mutagenesis is not suitable for all cell types, and can require substantial optimization for each application.

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