mutagenesis

American  

[myoo-tuh-jen-uh-sis] / ˌmyu təˈdʒɛn ə sɪs /

noun

1. the origin and development of a mutation.

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mutagenesis British  

/ ˌmjuːtəˈdʒɛnɪsɪs /

noun

1. genetics the generation, usually intentional, of mutations

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Other Word Forms

• mutagenetic adjective

Etymology

Origin of mutagenesis

From New Latin, dating back to 1950–55; mutation, -genesis

Example Sentences

The researchers used site-specific mutagenesis to gain new insights into how the cofactor precursor is integrated into the enzyme and how individual amino acids are involved in anchoring and synthesis.

From Science Daily

The paper, "Base editing mutagenesis maps functional alleles to tune human T cell activity," was published in Nature on December 13.

From Science Daily

"Xiangyu's comprehensive study of the structure highlights the advantage that a targeted, structurally guided approach has over large and costly random mutagenesis screening."

From Science Daily

“That is what we term lethal mutagenesis,” he adds.

From Scientific American

The use of this technique could be seen as a weakness of Wang and co-workers’ approach, because unnatural-amino-acid mutagenesis is not suitable for all cell types, and can require substantial optimization for each application.

From Nature