noun Pathology.

the replacement of bone marrow by fibrous tissue, characteristic of leukemia and certain other diseases.

Origin of myelofibrosis

First recorded in 1945–50; myelo- + fibrosis Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

myelofibrosis in Medicine




Fibrosis of the bone marrow associated with myeloid metaplasia, leukoerythroblastosis, and thrombocytopenia.myelosclerosis
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.