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Showing results for nondisjunction. Search instead for non-sanction.

nondisjunction

American  
[non-dis-juhngk-shuhn] / ˌnɒn dɪsˈdʒʌŋk ʃən /

noun

Biology.

  1. the failure of chromosomes to separate and segregate into daughter cells at division.

nondisjunction British  
/ ˌnɒndɪsˈdʒʌŋkʃən /

noun

  1. the failure of paired homologous chromosomes to move to opposite poles of the cell during meiosis

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of nondisjunction

First recorded in 1910–15; non- + disjunction

Vocabulary lists containing nondisjunction

Genetics - Middle School

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Genetics - High School

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Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Blocking glycolysis in RBCs interrupts the process of mitosis leading to nondisjunction.

From Textbooks • Jun. 9, 2022

They are caused by nondisjunction, which occurs when pairs of homologous chromosomes or sister chromatids fail to separate during meiosis.

From Textbooks • Jun. 9, 2022

The M checkpoint ensures the proper duplication of DNA and if it fails, the cells may undergo nondisjunction of chromosomes.

From Textbooks • Jun. 9, 2022

This mistake is known as nondisjunction, which means “not coming apart.”

From Textbooks • Jan. 1, 2018

The frequency of nondisjunction events appears to increase with age, so the frequency of bearing a child with Down syndrome increases in women over 36.

From Textbooks • Jun. 19, 2013

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023

Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.