[ si-stem-ik ]
/ sɪˈstɛm ɪk /


of or relating to a system.
Physiology, Pathology.
  1. pertaining to or affecting the body as a whole.
  2. pertaining to or affecting a particular body system.
(of a pesticide) absorbed and circulated by a plant or other organism so as to be lethal to pests that feed on it.

Origin of systemic

First recorded in 1795–1805; system + -ic

Related forms

sys·tem·i·cal·ly, adverbnon·sys·tem·ic, adjective

Can be confused

systematic systemic Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

British Dictionary definitions for non-systemic


/ (sɪˈstɛmɪk, -ˈstiː-) /


physiol (of a poison, disease, etc) affecting the entire body
(of a pesticide, fungicide, etc) spreading through all the parts of a plant and making it toxic to pests or parasites without destroying it


a systemic pesticide, fungicide, etc

Derived Forms

systemically, adverb
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Medicine definitions for non-systemic


[ sĭ-stĕmĭk ]


Of or relating to a system.
Of, relating to, or affecting the entire body or an entire organism.
Relating to or affecting a particular body system, especially the nervous system.
Relating to systemic circulation.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.