[ si-stem-ik ]
/ sɪˈstɛm ɪk /


of or relating to a system.
Physiology, Pathology.
  1. pertaining to or affecting the body as a whole.
  2. pertaining to or affecting a particular body system.
(of a pesticide) absorbed and circulated by a plant or other organism so as to be lethal to pests that feed on it.

Nearby words

  1. systematism,
  2. systematist,
  3. systematize,
  4. systematized delusion,
  5. systematology,
  6. systemic anaphylaxis,
  7. systemic availability,
  8. systemic circulation,
  9. systemic grammar,
  10. systemic linguistics

Origin of systemic

First recorded in 1795–1805; system + -ic

Related formssys·tem·i·cal·ly, adverbnon·sys·tem·ic, adjective

Can be confusedsystematic systemic Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

Examples from the Web for systemically

British Dictionary definitions for systemically


/ (sɪˈstɛmɪk, -ˈstiː-) /


physiol (of a poison, disease, etc) affecting the entire body
(of a pesticide, fungicide, etc) spreading through all the parts of a plant and making it toxic to pests or parasites without destroying it


a systemic pesticide, fungicide, etc
Derived Formssystemically, adverb

Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Word Origin and History for systemically



1803, irregularly formed from system, used in medicine and biology for differentiation of meaning from systematic. Related: Systemically.

Online Etymology Dictionary, © 2010 Douglas Harper

Medicine definitions for systemically


[ sĭ-stĕmĭk ]


Of or relating to a system.
Of, relating to, or affecting the entire body or an entire organism.
Relating to or affecting a particular body system, especially the nervous system.
Relating to systemic circulation.

The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.