- the power of enduring or resisting the action of a drug, poison, etc.: a tolerance to antibiotics.
- the lack of or low levels of immune response to transplanted tissue or other foreign substance that is normally immunogenic.
- the permissible range of variation in a dimension of an object.Compare allowance(def 8).
- the permissible variation of an object or objects in some characteristic such as hardness, weight, or quantity.
Origin of tolerance
Synonyms for tolerance
early 15c., "endurance, fortitude," from Old French tolerance (14c.), from Latin tolerantia "endurance," from tolerans, present participle of tolerare "to bear, endure, tolerate" (see toleration). Of authorities, in the sense of "permissive," first recorded 1530s; of individuals, with the sense of "free from bigotry or severity," 1765. Meaning "allowable amount of variation" dates from 1868; and physiological sense of "ability to take large doses" first recorded 1875.