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Northern blot

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noun

Biology, Medicine/Medical. a procedure for studying the activity of a specific gene, as in testing for a hereditary defect: RNA fragments in an extract of a cell population or a tissue are separated by gel electrophoresis, transferred to a filter, and then hybridized with labeled DNA or RNA derived from a laboratory-engineered copy of the gene in order to identify the size and abundance of the RNA expressed by that gene.

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Origin of Northern blot

First recorded in 1977; originally as a facetious counterpart to Southern blot
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2021

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