[noo-klee-uh-fil-ik, nyoo-]

adjective Chemistry.

of or relating to electron contribution in covalent bonding (opposed to electrophilic).

Nearby words

  1. nucleon,
  2. nucleon number,
  3. nucleonics,
  4. nucleopetal,
  5. nucleophile,
  6. nucleoplasm,
  7. nucleoprotein,
  8. nucleorrhexis,
  9. nucleosidase,
  10. nucleoside

Origin of nucleophilic

First recorded in 1930–35; nucleo- + -philic

Related formsnu·cle·o·phile [noo-klee-uh-fahyl, nyoo-] /ˈnu kli əˌfaɪl, ˈnyu-/, noun Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

British Dictionary definitions for nucleophile



chem having or involving an affinity for positive charge. Nucleophilic reagents (nucleophiles) are molecules, atoms, and ions that behave as electron donorsCompare electrophilic
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Medicine definitions for nucleophile




A chemical compound or group that is attracted to nuclei and tends to donate or share electrons.
Related formsnu′cle•o•philic (-fĭlĭk) adj.

The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.