osteoblast

American  

[os-tee-uh-blast] / ˈɒs ti əˌblæst /

noun

Anatomy.

1. a bone-forming cell.

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osteoblast British  

/ ˈɒstɪəʊˌblæst /

noun

1. a bone-forming cell

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osteoblast Scientific  

/ ŏs′tē-ə-blăst′ /

1. A specialized bone cell that produces and deposits the matrix that is needed for the development of new bone and consists primarily of collagen fibers. Osteoblasts are formed from osteoclasts on the outer surfaces of bone and in bone cavities, and bone deposition takes place constantly in living bone. As new bone grows and hardens with the addition of calcium and phosphate, osteoblasts become embedded in the bone matrix and develop into osteocytes.

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Other Word Forms

• osteoblastic
  adjective

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Etymology

Origin of osteoblast

First recorded in 1870–75; osteo- + -blast

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Compare meaning

How does osteoblast compare to similar and commonly confused words? Explore the most common comparisons:

• osteoblast vs. osteoclast
• osteoblast vs. osteocyte

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Example Sentences

See Examples For:

osteoblast

Notably, while PTH induction alone did not affect cell proliferation, Gprc5a knockdown resulted in an increase in the expression of cell-cycle-related genes and osteoblast differentiation markers.

From Science Daily ● Jun. 18, 2024

Overall, these findings reveal that Gprc5a -- a novel inducible target gene of PTH, negatively regulates osteoblast proliferation and differentiation, by partially suppressing BMP signaling.

From Science Daily ● Jun. 18, 2024

The researchers treated cultured mouse osteoblast cells and mice with teriparatide.

From Science Daily ● Jun. 18, 2024

A therapeutic drug that inhibits osteoblast activity would be useful.

From Textbooks ● Jun. 9, 2022

The development of the latter is simple, the connective tissue corpuscles functioning by a simple change of product as osteoblast.

From Text Book of Biology, Part 1: Vertebrata by H. G. (Herbert George) Wells

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