pathophysiology

American  

[path-oh-fiz-ee-ol-uh-jee] / ˌpæθ oʊˌfɪz iˈɒl ə dʒi /

noun

Pathology.

1. the physiology of abnormal or diseased organisms or their parts; the functional changes associated with a disease or syndrome.

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Etymology

Origin of pathophysiology

First recorded in 1950–55; patho- + physiology

Example Sentences

On an almost daily basis, we learned about the shape of virus evolution, details of disease ecology, and previously unknown vagaries of human pathophysiology.

From Salon • Apr. 9, 2025

“Unfortunately, we don’t know why. There is so much we don’t understand about the pathophysiology of what makes it more lethal for one animal than another.”

From Salon • Jun. 19, 2024

The study, which focuses on the role of reactive astrocytes and the plexin-B1 protein in Alzheimer's pathophysiology, provides crucial insights into brain cell communication and opens the door to innovative treatment strategies.

From Science Daily • May 27, 2024

This inhibited the expression of a group of target genes involved in fatty acid synthesis, polyunsaturated fatty acid synthesis and uptake, and lipoprotein secretion, which improved fatty liver pathophysiology, as observed in wild-type mice.

From Science Daily • Jan. 13, 2024

Interleukin-6 has been implicated in the pathophysiology of PMR because circulating elevated levels and increased tissue expression of interleukin-6 have been found in PMR patients.

From Science Daily • Oct. 25, 2023