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pepsin

American  
[pep-sin] / ˈpɛp sɪn /
Or pepsine

noun

Biochemistry.
  1. an enzyme, produced in the stomach, that in the presence of hydrochloric acid splits proteins into proteoses and peptones.

  2. a commercial form of this substance, obtained from the stomachs of hogs, used as a digestive, as a ferment in the manufacture of cheese, etc.


pepsin British  
/ ˈpɛpsɪn /

noun

  1. a proteolytic enzyme produced in the stomach in the inactive form pepsinogen, which, when activated by acid, splits proteins into peptones

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

pepsin Scientific  
/ pĕp′sĭn /
  1. Any of various digestive enzymes found in vertebrate animals that catalyze the hydrolysis of proteins to peptides.


Etymology

Origin of pepsin

1835–45; < Greek péps ( is ) digestion ( pep-, base of péptein to digest + -sis -sis ) + -in 2


Vocabulary lists containing pepsin

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Hydrochloric acid helps to convert the inactive pepsinogen to pepsin.

From Textbooks ● Jun. 9, 2022

Pepsin breaks peptide bonds and cleaves proteins into smaller polypeptides; it also helps activate more pepsinogen, starting a positive feedback mechanism that generates more pepsin.

From Textbooks ● Jun. 9, 2022

In the stomach, pepsinogen mixes with hydrochloric acid to form pepsin, which begins digesting proteins, such as turkey, into smaller chains of amino acids.

From Textbooks ● Jun. 9, 2022

An enzyme called pepsin digests protein in the stomach.

From Textbooks ● Jun. 9, 2022

The soft drink had been named for the digestive enzyme pepsin, he sagely told us, and so was suited to the task.

From "Middlesex: A Novel" by Jeffrey Eugenides

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