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noun Informal.
  1. sister.
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Origin of sis

1825–35, Americanism; shortened form; compare Dutch zus for zuster sister


  1. a suffix appearing in loanwords from Greek, where it was used to form from verbs abstract nouns of action, process, state, condition, etc.: thesis; aphesis.
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Origin of -sis

From Greek
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018

Related Words for sis

crony, comrade, buddy, playmate, amigo, sidekick, associate, chum, brother, homeboy, companion, mate, sister, homegirl, sis, pal, connate, amiga, bro, cuz

Examples from the Web for sis

Contemporary Examples of sis

Historical Examples of sis

British Dictionary definitions for sis


  1. informal short for sister
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  1. Southern African informal an exclamation of disgust
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Word Origin for sis

Afrikaans, possibly from Khoi


abbreviation for
  1. Also called: MI6 (in Britain) Secret Intelligence Service
  2. (in New Zealand) Security Intelligence Service
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Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Word Origin and History for sis


1650s, abbreviated form of sister; in American English, applied generally to girls and young women (1859). It also was the familiar short form of Cecilie, Cicely, a common name for girls in the Middle English period.

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suffix in Greek-derived nouns denoting action, process, state, condition, from Greek -sis, which is identical in meaning with Latin -entia, English -ing (1).

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Online Etymology Dictionary, © 2010 Douglas Harper