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phosphodiesterase

(fŏs′fō-dī-ĕstə-rās′, -rāz′)
n.
  1. Any of a class of enzymes that catalyze the cleaving of phosphodiester bonds, such as those between nucleotides in nucleic acids, to produce smaller nucleotide units or mononucleotides but not inorganic phosphate.
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The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.