phosphorylate
Americanverb (used with object)
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Etymology
Origin of phosphorylate
Example Sentences
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Interestingly, even in mice that don't produce CDKL5, there was still some EB2 phosphorylation taking place, which suggested that another similar enzyme must also be able to phosphorylate it.
From Science Daily ● Feb. 8, 2024
On the intracellular side, the ends of peptide chains on each protein phosphorylate the other member of the pair, providing active docking sites that initiate cellular responses.
From Textbooks ● Jun. 9, 2022
Various kinases are named for the substrate they phosphorylate.
From Textbooks ● Jun. 9, 2022
The authors discovered that mitochondrial dysfunction caused HRI to phosphorylate eIF2α even when haem was plentiful, which was surprising, given that HRI activation had been thought to depend on haem depletion11,12.
From Nature ● Mar. 3, 2020
In the final step, these protein kinases phosphorylate proteins in the cytoplasm.
From Textbooks ● Jun. 19, 2013
Most studies of phosphorylated α-synuclein have studied its role in certain neurological disorders such as Parkinson's disease and Lewy body dementia, where it builds up in protein clumps called Lewy bodies.
From Science Daily ● Jan. 9, 2024
Furthermore, they observed an association between increasing neural activity electrically or chemically and an increase in the amount of phosphorylated α-synuclein in both cultured cells and in mouse brain tissue.
From Science Daily ● Jan. 9, 2024
The researchers then focused on a specific phosphorylation site and created a mutation that prevented it from being phosphorylated.
From Scientific American ● Feb. 24, 2023
These are considered less accurate than imaging or spinal fluid tests that measure two types of proteins, beta-amyloid and phosphorylated tau, which accumulate abnormally in the brains of people with Alzheimer’s.
From Washington Post ● Sep. 15, 2022
In a phosphorylated state, the Na+/K+ pump has more free energy and is triggered to undergo a conformational change.
From Textbooks ● Jun. 9, 2022
Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.
