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polypeptide

American

[pol-ee-pep-tahyd, -tid] / ˌpɒl iˈpɛp taɪd, -tɪd /

noun

Biochemistry.

a chain of amino acids linked together by peptide bonds and having a molecular weight of up to about 10,000.

polypeptide British

/ ˌpɒlɪˈpɛptaɪd /

noun

any of a group of natural or synthetic polymers made up of amino acids chemically linked together; this class includes the proteins See also peptide

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

polypeptide Scientific

/ pŏl′ē-pĕp′tīd′ /

A peptide, such as a small protein, containing many molecules of amino acids, typically between 10 and 100.

Etymology

Origin of polypeptide

First recorded in 1900–05; poly- + peptide

Compare meaning

How does polypeptide compare to similar and commonly confused words? Explore the most common comparisons:

peptide vs. polypeptide

Vocabulary lists containing polypeptide

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Nutrition and Digestion - High School

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Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

polypeptide

The drug is described as glucagon-like peptide-1 receptor and gastric inhibitory polypeptide receptor dual agonist, with potential for once-weekly oral dosing.

From MarketWatch ● Sep. 29, 2026

The central bank expects demand for polypeptide hormones to steady in coming quarters, and has a similar outlook for GDP.

From The Wall Street Journal ● Jun. 18, 2026

Meanwhile, when NS3pro detects a viral polypeptide to cut, it forces the complex into the closed conformation, becoming a protease.

From Science Daily ● Dec. 8, 2023

Tirzepatide targets a second hormone, called glucose-dependent insulinotropic polypeptide, or GIP.

From Seattle Times ● Nov. 8, 2023

Given the X-ray data, a large variety of possible three- dimensional configurations for the polypeptide chain were quickly discarded.

From "Double Helix" by James D. Watson

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Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023