base editing

American  

[bays ed-it-ing] / ˈbeɪs ˌɛd ɪt ɪŋ /

noun

1. Genetics. a precise gene editing technique in which a single base or nucleotide (represented by a letter) is replaced by another in the sequence of a piece of DNA.

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Other Word Forms

• base editor
  noun
• base-edited
  adjective

Example Sentences

See Examples For:

base editing

Speaking of gene editing, Columbia University researchers successfully demonstrated base editing of “early human embryos” to replace specific genetic letters.

From The Wall Street Journal ● Jun. 21, 2026

A DNA-editing technique, base editing, was used on early-stage embryos to fix disease-causing mutations.

From The Wall Street Journal ● Jun. 5, 2026

With base editing, developed in 2016, researchers can engineer point mutations, but not all possible point mutations.

From Science Daily ● Mar. 12, 2024

Some clinicians are also concerned about another potential risk of base editing.

From Science Magazine ● Nov. 11, 2023

So there are already trials of base editing under way in sickle-cell disease, as well as high cholesterol that runs in families and the blood disorder beta-thalassemia.

From BBC ● Dec. 10, 2022