predisposed

American  

[pree-di-spohzd] / ˌpri dɪˈspoʊzd /

adjective

1. having or showing an inclination or tendency toward a specified condition, opinion, behavior, etc., beforehand.

   Many studies show how genes interact with the environment to cause disease in predisposed individuals.

   The novel is skillfully written, but in a style that requires close reading and a predisposed reader.

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verb

1. the simple past tense and past participle of predispose.

Other Word Forms

• predisposedly adverb
• predisposedness noun
• unpredisposed adjective

Etymology

Origin of predisposed

predispose ( def. ) + -ed ² ( def. )

Example Sentences

"Exosomes are used to communicate with and activate surrounding cells, and we have now identified a defect in both the production and the quality of exosomes in cells that we know are predisposed to Alzheimer's."

From Science Daily • Nov. 25, 2025

"Clearly, the authors of these papers are predisposed in favour of Nova since they created it," she said, adding that more research is needed to identify the exact mechanisms that UPFs could be causing harm.

From Barron's • Nov. 18, 2025

Most had had previous, less severe incidents—or “micro concussions”—that while not enough to send them to a clinician, predisposed them to a bigger event, he said.

From The Wall Street Journal • Sep. 14, 2025

But Lindhome is, by her own admission, naturally predisposed to find the positive in everything.

From Los Angeles Times • Apr. 7, 2025

Eisman was predisposed to suspect the worst of whatever Goldman Sachs might be doing with the debts of lower-middle-class Americans.

From "The Big Short" by Michael Lewis