prothrombin

American  

[proh-throm-bin] / proʊˈθrɒm bɪn /

noun

Biochemistry.

1. a plasma protein involved in blood coagulation that on activation by factors in the plasma is converted to thrombin.

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prothrombin British  

/ prəʊˈθrɒmbɪn /

noun

1. biochem a zymogen found in blood that gives rise to thrombin on activation See also phylloquinone

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prothrombin Scientific  

/ prō-thrŏm′bĭn /

1. A glycoprotein that is converted to thrombin during blood clotting. Prothrombin is formed by and stored in the liver.

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Etymology

Origin of prothrombin

First recorded in 1895–1900; pro- ¹ + thrombin

Example Sentences

They found I have a blood disorder called prothrombin gene mutation.

From Fox News

I had barely removed my coat before the doctor started rattling off the things I had tested negative for: antiphospholipid antibodies, lupus anticoagulant, Factor V Leiden, prothrombin gene mutation.

From The Guardian

We physicians should see a record of her prothrombin times to assess adequacy of control.

From Washington Post

Wrong prothrombin time results could cause doctors to prescribe too little or too much warfarin.

From The Wall Street Journal

Tests showed that she has a prothrombin gene mutation that, with estrogen, is a time bomb.

From Seattle Times