thrombin

American  

[throm-bin] / ˈθrɒm bɪn /

noun

Biochemistry.

1. an enzyme of the blood plasma that catalyzes the conversion of fibrinogen to fibrin, the last step of the blood clotting process.

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thrombin British  

/ ˈθrɒmbɪn /

noun

1. biochem an enzyme that acts on fibrinogen in blood causing it to clot

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thrombin Scientific  

/ thrŏm′bĭn /

1. An enzyme in blood that catalyzes the conversion of fibrinogen to fibrin and is essential to the coagulation of blood.

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Etymology

Origin of thrombin

First recorded in 1895–1900; thromb(us) + -in ²

Example Sentences

As a baseline test, the researchers developed a PEG hydrogel without the embedded thrombin and introduced the aptamer library, finding there were hardly any remaining aptamers in the gel after 60 hours.

From Science Daily • Oct. 16, 2023

We carried out experiments on genetically modified mice in which astrocytes released less of this thrombin inhibitor.

From Scientific American • Mar. 12, 2020

By silencing a gene for antithrombin, fitusiran enables a rise in the production of the enzyme thrombin, which helps the blood to clot.

From Nature • Oct. 15, 2019

It works by blocking thrombin, a blood enzyme involved with clotting.

From Reuters • Nov. 18, 2013

The last step in the change is the action of thrombin upon fibrinogen to form fibrin, and the clot is complete.

From Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 1 "Bisharin" to "Bohea" by Various