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provirus

American  
[proh-vahy-ruhs, proh-vahy-] / ˈproʊˌvaɪ rəs, proʊˈvaɪ- /

noun

  • proviruses
    plural
  1. a viral form that is incorporated into the genetic material of a host cell.


provirus British  
/ ˈprəʊˌvaɪrəs /

noun

  1. the inactive form of a virus in a host cell

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Noun Inflected Forms


Etymology

Origin of provirus

1945–50; pro- 1 + virus, on the model of prophage


Compare meaning

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Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

We looked for sequences that matched each HML-2 provirus in the genome and found 37 different HML-2 proviruses that were still active.

From Scientific American ● Oct. 19, 2022

Viruses insert their genomes into their hosts in the form of a provirus.

From Scientific American ● Oct. 19, 2022

Furthermore, each tissue sample also contained genetic material from at least one provirus that could still produce viral proteins.

From Scientific American ● Oct. 19, 2022

If this is so, it will be the first instance of such a provirus among higher animals.

From Time Magazine Archive

One partial explanation may lie in the ability of new "provirus" particles to remain undetected in cells, doing no evident damage until they are stimulated by chemicals or X rays.

From Time Magazine Archive

All 54 tissue samples we analyzed had some evidence of activity of one or more of these proviruses.

From Scientific American ● Oct. 19, 2022

There are around 30 different kinds of human endogenous retroviruses in people today, amounting to over 60,000 proviruses in the human genome.

From Scientific American ● Oct. 19, 2022

Even now, some of its proviruses within the human genome still retain the ability to make viral proteins.

From Scientific American ● Oct. 19, 2022

Over the past 15 years, researchers have tried to drain the reservoirs of HIV hiding in the chromosomes of infected people with drugs meant to prod the proviruses into producing new viruses.

From Science Magazine ● Jan. 12, 2022

Researchers have floated several ideas for accelerating the block-and-lock process, including using drugs that target the proviral genes and gum up transcription machinery or therapeutic vaccines that speed elimination of the transcribing proviruses.

From Science Magazine ● Jan. 12, 2022

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