renin

American  

[ree-nin] / ˈri nɪn /

noun

Biochemistry.

1. a proteolytic enzyme secreted by the kidneys that is involved in the release of angiotensin.

---

renin British  

/ ˈriːnɪn /

noun

1. a proteolytic enzyme secreted by the kidneys, which plays an important part in the maintenance of blood pressure

---

renin Scientific  

/ rē′nĭn,rĕn′ĭn /

1. A proteinase enzyme of high specificity that is released by the kidney and acts to raise blood pressure by activating angiotensin.

2. See also angiotensin

---

Etymology

Origin of renin

First recorded in 1890–95; ren(i)- + -in ²

Example Sentences

See Examples For:

renin

"This neuro-immune-endocrine cooperation synergistically promotes increased production of renin to maintain blood pressure homeostasis, but, on the other hand, severe arteriolar hypertrophy reduces the blood filtration function of the kidney."

From Science Daily ● Nov. 21, 2024

But long-term use can take a terrible toll on the kidney, causing scarring and other dramatic physical changes that shift the organ's focus from blood filtration to producing renin.

From Science Daily ● Nov. 21, 2024

Preliminary data from the Johns Hopkins team point to blood vessel stiffness and renin hormone levels in the blood as potential reasons for the lack of blood pressure variation in mice without the receptor.

From Science Daily ● Mar. 20, 2024

When angiotensinogen is cleaved by renin, it produces angiotensin I, which is then converted into angiotensin II in the lungs.

From Textbooks ● Jun. 9, 2022

Describe how renin promotes release of ADH and aldosterone.

From Textbooks ● Jun. 9, 2022