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rheumatoid arthritis

American  

noun

Pathology.
  1. a chronic autoimmune disease characterized by inflammation of the joints, frequently accompanied by marked deformities, and ordinarily associated with manifestations of a general, or systemic, affliction.


rheumatoid arthritis British  

noun

  1. a chronic disease of the musculoskeletal system, characterized by inflammation and swelling of joints (esp joints in the hands, wrists, knees, and feet), muscle weakness, and fatigue

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

rheumatoid arthritis Scientific  
/ ro̅o̅mə-toid′ /
  1. A chronic autoimmune disease characterized by progressive arthritis of several small or medium-sized joints, especially in the hands. Symptoms can include morning stiffness, joint swelling and weakness, and deformity and disability.


Etymology

Origin of rheumatoid arthritis

First recorded in 1855–60

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

During the period before rheumatoid arthritis developed, participants treated with abatacept reported improvements in symptoms such as joint pain and fatigue, along with better overall well-being.

From Science Daily • Jun. 1, 2026

They say the results provide important evidence that targeted immune therapies can delay rheumatoid arthritis in people at highest risk and support further research into preventive strategies for autoimmune conditions.

From Science Daily • Jun. 1, 2026

The latest analysis tracked participants for between four and eight years, making it one of the longest follow up studies ever conducted in people at risk of rheumatoid arthritis.

From Science Daily • Jun. 1, 2026

Researchers are testing the drug’s efficacy in patients with difficult-to-treat rheumatoid arthritis, also known as D2T RA; the treatment is delivered as a subcutaneous injection once a week.

From Barron's • May 20, 2026

The survival mechanism has become the enemy, as in such illnesses as lupus and rheumatoid arthritis that can attack organs, joints, even the brain.

From "A Deadly Wandering: A Mystery, a Landmark Investigation, and the Astonishing Science of Attention in the Digital Age" by Matt Richtel

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